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The 2023 study involved 4,488 participants, all of whom had a variant of the LRRK2 gene that put them at a higher risk for Parkinson’s disease. “The LRRK2 (leucine-rich repeat kinase 2) gene plays a significant role in the development of Parkinson’s disease, especially in familial and some sporadic cases of the disease,” explained Dr. Daniel Truong, neurologist and medical director of the Truong Neuroscience Institute at MemorialCare Orange Coast Medical Center in Fountain Valley, California (via Medical News Today).
After analyzing the participant’s self-reported average intake of caffeine, researchers found that non-caffeine-drinkers had an increased risk of Parkinson’s disease compared to carriers who were caffeine-drinkers.
Coffee’s preventative powers in relation to PD have been studied before, all the way back to 1968, to be specific. For example, a 2018 study published in Frontiers in Neuroscience seemed to suggest that caffeine offers protection against dopamine degeneration. There is also some science that points toward coffee’s gut-brain axis benefits and how the stimulant can protect your brain cells from inflammation and damage. Interestingly, while researching the health conditions coffee can help prevent, science has also delved into randomized controlled trials (considered the most highly regarded form of scientific study) involving people with PD to see if the beverage can help treat some of the symptoms associated with the disease. Here’s what happened.
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